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In March and April 2026, however, that interception rate fell to just over 1%

This is particularly crucial for individuals with a history of depression or anxiety, as initiating a new medication such as retatrutide can impact mood

The study findings support the overall ocular safety of this drug class, as the absolute frequency of events remained very low, occurring in 134 patients (0.065%) in the GLP-1 agonist cohort and 143 patients (0.07%) in the comparator cohort

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